CE certified for diagnostic use.The COVID-19 (SARS-CoV-2) IgG ELISA is intended for the qualitative determination of IgG class antibodies against SARS-CoV-2 in human serum or plasma to support the diagnosis of COVID-19 disease and constitutes a supplement to direct pathogen detection. In addition, serology can be used to collect epidemiological information on the prevalence of SARS-CoV-2.
Significance of N-Protein in COVID-19 (SARS-CoV-2) ELISAs
A significant factor for the diagnostic specificity and sensitivity of COVID-19 ELISAs is which antigen is used for coating.
The DEMEDITEC COVID-19 (SARS-CoV-2) ELISAs use the SARS-CoV-2 nucleocapsid protein (N protein) as antigen for the detection of antibodies to SARS-CoV-2.
N protein is a highly conserved antigen which has the advantage that it is abundant during the course of corona infection and stronger immune response in comparison to other antigen can be observed. Studies using ELISAs with different antigens, structural protein (S1), Receptor Binding Domain (RBD) and N protein reveal that ELISAs coated with N protein antigen
are more sensitive than S1 coated ELISAs in detecting antibodies in patients with mild course of disease and showed a stronger correlation with Plaque Reduction Neutralization Test (PRNT) titer. Although the N proteins show a high level of preservation with other corona viruses, cross-reactivity with other relevant corona viruses does not seem likely, as studies indicate no significant cross-reactivity with other viruses.
CE certified for diagnostic use. The COVID-19 (SARS-CoV-2) IgM ELISA is intended for the qualitative determination of IgM class antibodies against SARS-CoV-2 in human serum or plasma to support the diagnosis of COVID-19 disease and constitutes a supplement to direct pathogen detection. In addition, serology can be used to collect epidemiological information on the prevalence of SARS-CoV-2.
Significance of N-Protein in COVID-19 (SARS-CoV-2) ELISAs
A significant factor for the diagnostic specificity and sensitivity of COVID-19 ELISAs is which antigen is used for coating.
The DEMEDITEC COVID-19 (SARS-CoV-2) ELISAs use the SARS-CoV-2 nucleocapsid protein (N protein) as antigen for the detection of antibodies to SARS-CoV-2.
N protein is a highly conserved antigen which has the advantage that it is abundant during the course of corona infection and stronger immune response in comparison to other antigen can be observed. Studies using ELISAs with different antigens, structural protein (S1), Receptor Binding Domain (RBD) and N protein reveal that ELISAs coated with N protein antigen are more sensitive than S1 coated ELISAs in detecting antibodies in patients with mild course of disease and showed a stronger correlation with Plaque Reduction Neutralization Test (PRNT) titer. Although the N proteins show a high level of preservation with other corona viruses, cross-reactivity with other relevant corona viruses does not seem likely, as studies indicate no significant cross-reactivity with other viruses.
CE certified for diagnostic use.The COVID-19 (SARS-CoV-2) IgA ELISA is intended for the qualitative determination of IgA class antibodies against SARS-CoV-2 in human serum or plasma to support the diagnosis of COVID-19 disease and constitutes a supplement to direct pathogen detection. In addition, serology can be used to collect epidemiological information on the prevalence of SARS-CoV-2.
Significance of N-Protein in COVID-19 (SARS-CoV-2) ELISAs
A significant factor for the diagnostic specificity and sensitivity of COVID-19 ELISAs is which antigen is used for coating.
The DEMEDITEC COVID-19 (SARS-CoV-2) ELISAs use the SARS-CoV-2 nucleocapsid protein (N protein) as antigen for the detection of antibodies to SARS-CoV-2.
N protein is a highly conserved antigen which has the advantage that it is abundant during the course of corona infection and stronger immune response in comparison to other antigen can be observed. Studies using ELISAs with different antigens, structural protein (S1), Receptor Binding Domain (RBD) and N protein reveal that ELISAs coated with N protein antigen are more sensitive than S1 coated ELISAs in detecting antibodies in patients with mild course of disease and showed a stronger correlation with Plaque Reduction Neutralization Test (PRNT) titer.
Although the N proteins show a high level of preservation with other corona viruses, cross-reactivity with other relevant corona viruses does not seem likely, as studies indicate no significant cross-reactivity with other viruses.
Interleukin 6 human ELISA kit
96 well ELISA microplate
...
£479.00
COVID-19 Antibody ELISA | Rapid PCR Assay Development | JR Biomedical UK
COVID-19 ELISA test kits | Point of care tests | Immunology research
JR Biomedical Ltd is a UK developer, manufacturer and distributor of medical diagnostics including ELISA kits and immunoassay reagents for research and clinical diagnostic use. Our customers include universities, research institutes and NHS laboratories. We also develop and manufacture high quality immunoassay reagents for ELISA under contract for specific pharmaceutical and vaccine applications.
- Full technical support and same day order processing
- Manufactured by ISO13485 certified European laboratories
- ELISA kits for diagnostic use are CE accredited according to the IVD Directive 98/79EC
- ISO 13485:2016 and ISO 9001:2015 accredited
- UK distributor for Demeditec Diagnostics ELISA kits and Milenia Biotec point of care diagnostics
Ordering information
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